English Français العربية

io.github.pkotecha-eng/aria-mcp-server

Official registry Health

Search 35M+ PubMed, 400K+ ClinicalTrials.gov & ISRCTN trials. Prompts included. No API key.

Source code Documentation

What can you do with io.github.pkotecha-eng/aria-mcp-server?

  • Life sciences researchers needing real-time literature access
  • Clinical trial coordinators checking eligibility and recruiting status
  • Drug discovery teams cross-referencing published evidence with active trials
  • Any Claude agent needing grounded biomedical knowledge

Install

Add this to your client's MCP configuration (Claude Desktop: claude_desktop_config.json; Cursor: .cursor/mcp.json; VS Code and others use the same "mcpServers" shape).

PYPI package aria-mcp-server
Claude Code 
claude mcp add aria-mcp-server -- uvx aria-mcp-server==0.2.1
JSON configuration (Claude Desktop, Cursor, VS Code) 
{
    "mcpServers": {
        "aria-mcp-server": {
            "command": "uvx",
            "args": [
                "aria-mcp-server==0.2.1"
            ]
        }
    }
}

Documentation

From the project's README on GitHub, refreshed weekly. Links open on GitHub.

Contents
  1. 🧬 ARIA Clinical Research MCP Server
  2. Tools
  3. Prompts
  4. Resources
  5. Example queries
  6. Quickstart
  7. Connect to Claude Desktop
  8. Data sources
  9. Tech stack
  10. Use cases
  11. Project Structure
  12. Built by

🧬 ARIA Clinical Research MCP Server

A standalone MCP server that gives any Claude agent real-time access to biomedical literature and clinical trials — no API keys required.

Tools

ToolDescription
search_pubmedSearch 35M+ peer-reviewed papers via NCBI E-utilities
search_clinical_trialsSearch 400K+ trials via ClinicalTrials.gov v2 API
search_isrctnSearch UK/European trials via ISRCTN registry

Prompts

PromptDescription
clinical-research-briefComprehensive evidence + trial brief for a condition
adverse-event-analysisStructured AE and safety profile for a drug
trial-eligibility-checkerPatient eligibility assessment across recruiting trials

Resources

ResourceDescription
info://ariaOverview of ARIA capabilities and data sources
reference://trial-phasesPhase I–IV definitions and FDA special designations
reference://high-impact-journalsCurated high-impact journals by specialty
reference://fda-databasesFDA databases for drug, safety, and regulatory research

Example queries

Once connected, ask Claude:

  • "Search PubMed for ketogenic diet pediatric epilepsy outcomes"
  • "Find recruiting trials for lung cancer immunotherapy"
  • "What does the literature say about veliparib in ovarian cancer, and are there active trials?"
  • "Find UK and European trials for pediatric epilepsy via ISRCTN"

Quickstart

pip install aria-mcp-server
aria-mcp-server

Connect to Claude Desktop

Add to ~/Library/Application Support/Claude/claude_desktop_config.json:

{
  "mcpServers": {
    "aria-clinical-research": {
      "command": "aria-mcp-server"
    }
  }
}

Restart Claude Desktop. The server will appear under Settings → Developer → Local MCP Servers.

Data sources

  • PubMed — NCBI E-utilities (public API, no key required)
  • ClinicalTrials.gov — v2 REST API (public API, no key required)
  • ISRCTN — UK/European clinical trials registry (public API, no key required)

Tech stack

  • FastMCP — MCP server framework
  • Python 3.12+

Use cases

  • Life sciences researchers needing real-time literature access
  • Clinical trial coordinators checking eligibility and recruiting status
  • Drug discovery teams cross-referencing published evidence with active trials
  • Any Claude agent needing grounded biomedical knowledge

Project Structure

aria-mcp-server/          ← root, where mcp-publisher runs
├── aria_mcp_server/      ← Python package
│   ├── __init__.py
│   ├── server.py
│   └── tools.py
├── server.json           ← MCP registry metadata
├── pyproject.toml
├── README.md
├── LICENSE
└── glama.json

Built by

Pooja Kotecha · dinq.me/pkotecha-eng

Frequently asked questions

What is io.github.pkotecha-eng/aria-mcp-server?

Search 35M+ PubMed, 400K+ ClinicalTrials.gov & ISRCTN trials. Prompts included. No API key.

How do I install io.github.pkotecha-eng/aria-mcp-server?

It runs on your machine. In Claude Code: claude mcp add aria-mcp-server -- uvx aria-mcp-server==0.2.1. For other clients, paste the JSON configuration from this page into their MCP settings.

Does io.github.pkotecha-eng/aria-mcp-server need an API key?

Its registry entry lists no required key or secret. Some features may still need an account with the service it connects to.

Is io.github.pkotecha-eng/aria-mcp-server open source?

Yes. Its code is on GitHub under the MIT license.

Who maintains io.github.pkotecha-eng/aria-mcp-server?

It is published by pkotecha-eng. AI.tn lists it but does not maintain or endorse it.

From the official MCP Registry. Listing is not an endorsement: review a server's code and permissions before giving it access to your data.