Pombase

Official registry Data and databases

PomBase MCP — the fission yeast (Schizosaccharomyces pombe) model-organism database.

Install

Add this to your client's MCP configuration (Claude Desktop: claude_desktop_config.json; Cursor: .cursor/mcp.json; VS Code and others use the same "mcpServers" shape).

Remote (streamable-http)
Claude Code
claude mcp add --transport http pombase 'https://gateway.pipeworx.io/pombase/mcp'
JSON configuration (Claude Desktop, Cursor, VS Code)
{
    "mcpServers": {
        "pombase": {
            "type": "http",
            "url": "https://gateway.pipeworx.io/pombase/mcp"
        }
    }
}

Documentation

From the project's README on GitHub, refreshed weekly. Links open on GitHub.

Contents
  1. mcp-pombase
  2. Tools
  3. Quick Start
  4. No MCP client? Call it over HTTP
  5. Standalone (no gateway account)
  6. Using with ask_pipeworx
  7. More
  8. License

mcp-pombase

PomBase MCP — the fission yeast (Schizosaccharomyces pombe) model-organism database.

Part of Pipeworx — an MCP gateway connecting AI agents to 1683+ live data sources.

Tools

ToolDescription
get_genePomBase (fission yeast / S. pombe model-organism DB): look up a gene by its PomBase systematic id and return its product, protein domains (InterPro), deletion viability, UniProt id, and curation status. Keyless. NOTE: requires a systematic id like "SPAC1002.01" or "SPBC2F12.13" — standard gene names like "cdc2" are NOT resolved by this API. Complements SGD (budding yeast).
get_referencePomBase: look up a curated S. pombe publication by its PubMed id (e.g. "PMID:11739790") and return its title, citation, authors, year, abstract, and how many genes it annotates. Keyless.

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "pombase": {
      "url": "https://gateway.pipeworx.io/pombase/mcp"
    }
  }
}
What this endpoint actually serves

tools/list at https://gateway.pipeworx.io/pombase/mcp returns the tools in the table above plus the shared Pipeworx meta-tools — ask_pipeworx, discover_tools, search_within, remember/recall and the rest of the gateway-wide set. So the tool count you see is larger than this table: a single-pack endpoint currently lists roughly 30 shared tools alongside the pack's own. The connection's initialize response states its exact scope, and is the authoritative answer for a given day.

This is deliberate, not multiplexing by accident. The meta-tools are what let a scoped connection answer a question this pack does not cover — via ask_pipeworx, which routes across the whole catalog — without you adding a second MCP server. There is currently no way to mount a pack endpoint without them; if the extra schemas cost you more context than the routing is worth, connect to the full gateway once rather than to several pack endpoints.

Or connect to the full Pipeworx gateway to get every pack's tools listed directly, instead of just this one's:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Both URLs reach the same gateway and the same 1683+ data sources. The only difference is which pack's tools are listed directly; ask_pipeworx reaches all of them from either one.

No MCP client? Call it over HTTP

curl -X POST https://gateway.pipeworx.io/v1/tools/pombase_get_gene \
  -H 'Content-Type: application/json' \
  -d '{"id":"SPAC1002.01"}'

No account needed for the first calls. Inspect any tool: GET https://gateway.pipeworx.io/v1/tools/pombase_get_gene. Find one: POST https://gateway.pipeworx.io/v1/tools/search_packs with {"query":"..."}.

Standalone (no gateway account)

This package also runs as a local stdio MCP server — no Pipeworx account, no gateway round-trip:

{
  "mcpServers": {
    "pombase": {
      "command": "npx",
      "args": ["-y", "@pipeworx/mcp-pombase"]
    }
  }
}

Or run it directly to confirm it starts:

npx -y @pipeworx/mcp-pombase

It speaks MCP over stdin/stdout and answers initialize/tools/list/tools/call for only this pack's tools — none of the shared meta-tools the gateway connection above adds. Same source, same tools, no ask_pipeworx routing.

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English — this works on the pack endpoint above as well as on the full gateway:

ask_pipeworx({ question: "your question about Pombase data" })

The gateway picks the right tool and fills the arguments automatically.

More

License

MIT

Frequently asked questions

What is Pombase?

PomBase MCP — the fission yeast (Schizosaccharomyces pombe) model-organism database.

How do I install Pombase?

It runs as a remote server. In Claude Code: claude mcp add --transport http pombase 'https://gateway.pipeworx.io/pombase/mcp'. For other clients, paste the JSON configuration from this page into their MCP settings.

Does Pombase need an API key?

Its registry entry lists no required key or secret. Some features may still need an account with the service it connects to.

Is Pombase open source?

Yes. Its code is on GitHub under the MIT license.

Who maintains Pombase?

It is published by pipeworx-io. AI.tn lists it but does not maintain or endorse it.

From the official MCP Registry. Listing is not an endorsement: review a server's code and permissions before giving it access to your data.