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Appendix

Official registry Health

Physician-reviewed medical opinions and prescriptions for AI agents.

Source code Website Documentation

Install

Add this to your client's MCP configuration (Claude Desktop: claude_desktop_config.json; Cursor: .cursor/mcp.json; VS Code and others use the same "mcpServers" shape).

Remote (streamable-http)
Claude Code 
claude mcp add --transport http appendix 'https://mcp.appendix.com/mcp'
JSON configuration (Claude Desktop, Cursor, VS Code) 
{
    "mcpServers": {
        "appendix": {
            "type": "http",
            "url": "https://mcp.appendix.com/mcp"
        }
    }
}

Documentation

From the project's README on GitHub, refreshed weekly. Links open on GitHub.

Contents
  1. Appendix MCP Server
  2. Installation
  3. Available Tools
  4. Development
  5. Environment Variables
  6. Endpoints

Appendix MCP Server

Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one.

Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.

Use the Appendix MCP server to search medical literature, submit clinical encounters, and receive clinical guidance and prescriptions from board-certified physicians. Learn more at appendix.com.

Installation

Claude Code
claude mcp add --transport http appendix https://mcp.appendix.com/mcp
Claude Desktop / Claude Web Connectors

Add to your Claude Desktop config (claude_desktop_config.json) or Claude.ai custom-connector form:

{
  "mcpServers": {
    "appendix": {
      "url": "https://mcp.appendix.com/mcp"
    }
  }
}
Other clients
ClientURL
Claude Code, Claude Desktop, Claude.ai connectorshttps://mcp.appendix.com/mcp
Anthropic Messages API (mcp_servers)https://mcp.appendix.com/mcp

The server speaks Streamable HTTP only — the current MCP spec transport (2025-03-26).

Available Tools

ToolDescription
search_knowledge_baseSearch medical literature and treatment guidelines
submit_encounterSubmit a clinical letter for physician review
list_conditionsList available conditions and medications

Development

npm install
npm run build
npm start

Watch mode:

npm run dev

Environment Variables

VariableDefaultDescription
API_BASE_URLhttps://api.appendix.comAppendix API base URL
PORT3001HTTP listener port

Endpoints

MethodPathPurpose
GET/healthHealth probe for the hosting platform
POST GET DELETE/mcpStreamable HTTP transport (stateless mode)

Frequently asked questions

What is Appendix?

Physician-reviewed medical opinions and prescriptions for AI agents.

How do I install Appendix?

It runs as a remote server. In Claude Code: claude mcp add --transport http appendix 'https://mcp.appendix.com/mcp'. For other clients, paste the JSON configuration from this page into their MCP settings.

Does Appendix need an API key?

Its registry entry lists no required key or secret. Some features may still need an account with the service it connects to.

Is Appendix open source?

Its code is public on GitHub, but the repository does not declare a standard license.

Who maintains Appendix?

It is published by appendixhealth. AI.tn lists it but does not maintain or endorse it.

From the official MCP Registry. Listing is not an endorsement: review a server's code and permissions before giving it access to your data.